ATX inhibitor 26
ATX inhibitor 26 is an Autotaxin (ATX) inhibitor with an IC50 of 57 nM in human plasma. It effectively inhibits cell migration and collagen gel contraction. Additionally, ATX inhibitor 26 demonstrates significant antifibrotic activity, reducing collagen deposition in a Bleomycin (BLM) -induced pulmonary fibrosis model.
Product Specifications
CAS Number
2940248-11-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (OCC=1C=C (Cl) C=C (Cl) C1) N2CCC (C3=NN=C (O3) NCC4=CN=NN4) CC2
Molecular Formula
C18H19Cl2N7O3
Molecular Weight
452.30
Storage Conditions
-20°C
Notes
For research use only.
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