BCX-3607
BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor with an IC50 of 4 nM. By inhibiting the TF-FVIIa complex, it effectively blocks the extrinsic coagulation pathway and significantly prolongs prothrombin time (PT) . BCX-3607 exhibits higher selectivity for TF-FVIIa over other serine proteases like thrombin and FXa. It reduces thrombus weight and inflammation, offering dual anti-thrombotic and anti-inflammatory effects. BCX-3607 is applicable in research on thrombosis-related diseases.
Product Specifications
CAS Number
885684-79-7
Smiles
O=C (O) C1=CC (=CC=C1C=2C=CC (C=C) =CC2CNC3=NC=C (C=C3) C (=N) N) C (=O) NCC (C) C
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
Storage Conditions
-20°C
Notes
For research use only.
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