Rho GTPase inhibitor 1
Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.
Product Specifications
CAS Number
1309252-99-0
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology; Pharmacology & Drug Discovery
Smiles
N1=CC=2C=CC=CC2C (=C1) C3=CC=CC4=C3OC (CN) C4
Molecular Formula
C18H16N2O
Molecular Weight
276.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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