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Rho GTPase inhibitor 1

Rho GTPase inhibitor 1 (compound 7) is a potent inhibitor of Rho GTPase. It exhibits high affinity for Cdc42, Rac1, and RhoA, with dissociation constants (KDs) of 151 μM, 352 μM, and 232 μM, respectively. Additionally, Rho GTPase inhibitor 1 reduces cell migration in glioblastoma cell lines.

Product Specifications

CAS Number

1309252-99-0

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology; Pharmacology & Drug Discovery

Smiles

N1=CC=2C=CC=CC2C (=C1) C3=CC=CC4=C3OC (CN) C4

Molecular Formula

C18H16N2O

Molecular Weight

276.33

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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