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Insecticidal agent 24

Insecticidal agent 24 is an orally active pyridinyl spiroindoline lead compound. It demonstrates antimalarial activity with Pf NF54IC50 of 0.08 μM. Insecticidal agent 24 also inhibits hERG activity with an IC50 of 6.5 μM. In a humanized immunodeficient NSG mouse model of malaria infection, it effectively reduces parasitemia.

Product Specifications

Field of Research

Infectious Disease & Virology

Molecular Formula

C26H29N3O2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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