PDE4B-IN-4
PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM) . It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS) -induced sepsis.
Product Specifications
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Smiles
O=C1NC (N/N=C/C2=CC=C (OC) C (OC) =C2) =NC (C3=CC (OC4CCCC4) =C (OC) C=C3) =C1C#N
Molecular Formula
C26H27N5O5
Molecular Weight
489.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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