GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.
Product Specifications
Field of Research
Neuroscience, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Smiles
ClC1=CC=C (CN (C (/C=C\C (NC2=NNC (C) =C2) =O) =O) C) C=C1
Molecular Formula
C16H17ClN4O2
Molecular Weight
332.79
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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