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GSK-3β inhibitor 27

GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.

Product Specifications

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Smiles

ClC1=CC=C (CN (C (/C=C\C (NC2=NNC (C) =C2) =O) =O) C) C=C1

Molecular Formula

C16H17ClN4O2

Molecular Weight

332.79

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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