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DEG-35

DEG-35 is a CRBN-dependent bifunctional degrader targeting IKZF2 and CK1α, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. It activates the p53 apoptotic pathway and is applicable for research related to acute myeloid leukemia (AML) .

Product Specifications

CAS Number

2734910-37-1

Field of Research

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

O=C (NC1=CC=C2C (=O) N (CC2=C1) C3C (=O) NC (=O) CC3) C4=CC=C5C=C (OC) C=CC5=C4

Molecular Formula

C25H21N3O5

Molecular Weight

443.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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