DEG-35
DEG-35 is a CRBN-dependent bifunctional degrader targeting IKZF2 and CK1α, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. It activates the p53 apoptotic pathway and is applicable for research related to acute myeloid leukemia (AML) .
Product Specifications
CAS Number
2734910-37-1
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Smiles
O=C (NC1=CC=C2C (=O) N (CC2=C1) C3C (=O) NC (=O) CC3) C4=CC=C5C=C (OC) C=CC5=C4
Molecular Formula
C25H21N3O5
Molecular Weight
443.45
Storage Conditions
-20°C
Notes
For research use only.
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