Lazertinib mesylate
Lazertinib (mesylate) (YH25448 (mesylate) ; GNS-1480 (mesylate) ) is an orally active EGFR inhibitor capable of crossing the blood-brain barrier. It suppresses the p-EGFR, p-AKT, and p-ERK signaling pathways, leading to apoptosis. Lazertinib (mesylate) demonstrates antitumor activity in the H1975-luc BM xenograft model in mice and is applicable for researching non-small cell lung cancer.
Product Specifications
CAS Number
2247995-37-3
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=C (C=C) NC1=CC (NC2=NC=CC (=N2) N3N=C (C=4C=CC=CC4) C (=C3) CN (C) C) =C (OC) C=C1N5CCOCC5.O=S (=O) (O) C
Molecular Formula
C31H38N8O6S
Molecular Weight
650.75
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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