JV8
JV8 is a BRD4 PROTAC degrader that facilitates ubiquitination and degradation of BRD4, inducing apoptosis (Apoptosis) . It exhibits antitumor activity in a mouse 4T1 orthotopic tumor model.
Product Specifications
CAS Number
2841716-61-6
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOCCOCC (N[C@@H] (C (=O) N4[C@H] (C (N[C@@H] (C) C5=CC=C (C=C5) C6=C (C) N=CS6) =O) C[C@@H] (O) C4) [C@@] (C) (C) C) =O) =O) N=C2C7=CC=C (Cl) C=C7) =NN=C3C) SC1C
Molecular Formula
C50H62ClN9O8S2
Molecular Weight
1016.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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