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TFAP4/Wnt/β-catenin-IN-1

TFAP4/Wnt/β-catenin-IN-1 (Compound A61) is an orally active inhibitor targeting the TFAP4/Wnt/β-catenin pathway. Known for its potent anticancer properties, it effectively targets various cancer cells, including those of gastric, lung, and breast cancer, with the strongest activity observed in MGC-803 gastric cancer cells (IC50: 3.92 μM) . By inhibiting the TFAP4/Wnt/β-catenin signaling pathway, it induces apoptosis and S phase cell cycle arrest. TFAP4/Wnt/β-catenin-IN-1 is applicable for gastric cancer research.

Product Specifications

Field of Research

Cancer Biology; Stem Cell & Developmental Biology, Signal Transduction, Stem Cell & Developmental Biology

Molecular Formula

C27H33BrN2O3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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