Axl-IN-19
Axl-IN-19 (Compound 68) is a selective inhibitor of AXL, a membrane-bound receptor tyrosine kinase, with an IC50 of 5.3 nM and a cellular KD of 6.8 nM. In rats, Axl-IN-19 demonstrates favorable pharmacokinetic properties, featuring low clearance and moderate bioavailability, and is applicable for cancer research.
Product Specifications
CAS Number
2870696-46-9
Field of Research
Signal Transduction
Smiles
C (N (C) C) (=O) C1=CC=C (C=2C3=CC (C=4C=C5CC[C@@H] (N6C7CC6COC7) CCC5=CC4) =CN=C3NN2) C=C1
Molecular Formula
C31H33N5O2
Molecular Weight
507.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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