Amyloid-β-IN-2
Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.
Product Specifications
CAS Number
1603833-55-1
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
C (NC1=CC (F) =CC (F) =C1) (=O) C2=CC=3C (N2) =CC=C (C3) [C@@H]4CN (C (C) =O) CCC4
Molecular Formula
C22H21F2N3O2
Molecular Weight
397.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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