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Amyloid-β-IN-2

Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.

Product Specifications

CAS Number

1603833-55-1

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Smiles

C (NC1=CC (F) =CC (F) =C1) (=O) C2=CC=3C (N2) =CC=C (C3) [C@@H]4CN (C (C) =O) CCC4

Molecular Formula

C22H21F2N3O2

Molecular Weight

397.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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