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ATX inhibitor 27

ATX inhibitor 27 (Compound 31) is an ATX inhibitor. It demonstrates IC50 values of 13 nM against human autotaxin (hATX) and 23 nM against lysophosphatidylcholine (LPC) . By inhibiting the ATX enzyme, ATX inhibitor 27 reduces LPA levels in the body. This compound is applicable in research related to ATX-LPA-associated conditions such as inflammation, neurodegenerative disorders, and cancer.

Product Specifications

CAS Number

2023027-81-6

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Smiles

N#CC1=CC=C (C=C1Cl) CN (C (=O) CN2C=NC=3C=CC (=CC3C2=O) C4CCN (C (=O) C) CC4) C

Molecular Formula

C26H26ClN5O3

Molecular Weight

491.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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