IKZF2-degrader 1
IKZF2-degrader 1 (Compound 31) is a molecular glue-type degrader of IKZF2 with a DC50 of 0.5 nM. It exhibits relatively low degradation activity against CK1α, with a DC50 of 210 nM. This compound is applicable in research focused on IKZF2-dependent cancers.
Product Specifications
CAS Number
2983840-43-1
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C4=NC=5C (=NNC5C (=C4) CN6CCCC6) NC (C) C) C (F) =C3C2) CC1
Molecular Formula
C27H30FN7O3
Molecular Weight
519.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
406686-01 50 µL
MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3, Germinal Center Kinase-Related Protein Kinase, GLK, MAPK/ERK Kinase Kinase Kinase 3, MEK Kinase Kinase 3, MEKKK 3, RAB8IPL1)
Sign In for Pricing
View Details 406686-02 100 µL
MAP4K3 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3, Germinal Center Kinase-Related Protein Kinase, GLK, MAPK/ERK Kinase Kinase Kinase 3, MEK Kinase Kinase 3, MEKKK 3, RAB8IPL1)
Sign In for Pricing
View Details 