EGFR-IN-158
EGFR-IN-158 (compound 12e) is an orally active EGFR inhibitor with an IC50 value of 0.22 nM for EGFR (Del19/T790M) . By binding to EGFR, EGFR-IN-158 inhibits phosphorylation and downstream signaling, thereby suppressing the proliferation of tumor cell lines and promoting apoptosis.
Product Specifications
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Molecular Formula
C27H35ClN8O4S
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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