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EGFR-IN-158

EGFR-IN-158 (compound 12e) is an orally active EGFR inhibitor with an IC50 value of 0.22 nM for EGFR (Del19/T790M) . By binding to EGFR, EGFR-IN-158 inhibits phosphorylation and downstream signaling, thereby suppressing the proliferation of tumor cell lines and promoting apoptosis.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Molecular Formula

C27H35ClN8O4S

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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