PLK1-IN-15
PLK1-IN-15 is a PLK1 inhibitor with an IC50 of 38.5 nM. It exhibits antiproliferative effects on HepG2, Huh7, H1299, and A549 cells, with IC50 values of 2.03, 2.08, 4.79, and 17.11 μM, respectively. Additionally, PLK1-IN-15 can induce cell cycle arrest in the G2/M phase and trigger apoptosis (Apoptosis), demonstrating anticancer activity.
Product Specifications
CAS Number
3068529-37-0
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C (OC) C1=C (SC2=C1CCCC2) NC3=NC (=NC=C3N (=O) =O) NC4=CC=C (C=C4) N5CCN (C) CC5
Molecular Formula
C25H29N7O4S
Molecular Weight
523.61
Storage Conditions
-20°C
Notes
For research use only.
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