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STING-IN-15

STING-IN-15 (compound 66) is a potent STING inhibitor, effectively suppressing human and mouse STING with IC50 values of 116 nM and 96.3 nM, respectively. In the REX1 D18N mouse model, STING-IN-15 significantly reduces tissue damage and inflammation.

Product Specifications

CAS Number

2912492-05-6

Field of Research

Cell Biology, Immunology & Inflammation

Smiles

N (C (NC=1C=C2C (=CC1) OC (F) (F) O2) =O) C=3C=4C (NC3) =CC=C (/C=C/CC#N) C4

Molecular Formula

C20H14F2N4O3

Molecular Weight

396.35

Storage Conditions

-20°C

Notes

For research use only.

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4- (2-chloro-4-methoxy-5-methylphenyl) -N-[ (1A) -2-cyclopropyl-1- (3-fluoro-4-methylphenyl) ethyl]-5-methyl-N- (2-propyn-1-yl) -2-thiazolamine
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4- (2-chloro-4-methoxy-5-methylphenyl) -N-[ (1A) -2-cyclopropyl-1- (3-fluoro-4-methylphenyl) ethyl]-5-methyl-N- (2-propyn-1-yl) -2-thiazolamine
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4- (2-chloro-4-methoxy-5-methylphenyl) -N-[ (1A) -2-cyclopropyl-1- (3-fluoro-4-methylphenyl) ethyl]-5-methyl-N- (2-propyn-1-yl) -2-thiazolamine
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