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FGFR-IN-18

FGFR-IN-18 (Compound KF7) is a covalent inhibitor targeting lysine on FGFR, exhibiting IC50 values of 1.1 nM for FGFR2, 1.3 nM for FGFR1, and 31.5 nM for FGFR4. It also shows affinity for FGFR3, with an inhibition rate of 52% at 10 nM. FGFR-IN-18 covalently modifies Lys485, a reactive site on FGFR.

Product Specifications

Field of Research

Cardiovascular Research, Signal Transduction

Molecular Formula

C32H37N9O6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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