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Orexin 2 Receptor Agonist 3

Orexin 2 Receptor Agonist 3 is an orally active and brain-penetrant agonist of the orexin receptor 2 (OX2) with an EC50 value of 2.5 nM. This compound increases wakefulness in both orexin/ataxin-3 NT1 mouse models and healthy Beagle dogs. It is applicable for research related to narcolepsy.

Product Specifications

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

FC1=C ([C@H] (C (NC2 (C3) CC3 (C) C2) =O) N (C4CC5 (CC5) C4) C (CC6=C (C7=NN (C) N=N7) ON=C6) =O) C=C (F) C=C1

Molecular Formula

C27H29F2N7O3

Molecular Weight

537.56

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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