CM112
CM112 is a selective degrader of protein arginine methyltransferase 1 (PRMT1), which connects a hydrophobic adamantane tag to MS023 via a 5-PEG linker. It induces the degradation of PRMT1 in various solid tumor cell lines. CM112 also targets the non-enzymatic functions of PRMT1 by reducing the stability of the orphan receptor TR3. This compound shows potential for cancer research.
Product Specifications
Field of Research
Epigenetics & Chromatin
Molecular Formula
C39H61N5O7
Storage Conditions
-20°C
Notes
For research use only.
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