(R) - (–) -Pirlindole mesylate
(R) - (–) -Pirlindole acts as a monoamine oxidase A (MAO-A) inhibitor with an IC50 value of 0.43 μM, exhibiting selectivity for MAO-A compared to MAO-B. When administered at 50 mg/kg, it reduces immobility time in the forced swim test in mice and, at 25 mg/kg, inhibits reserpine-induced palpebral ptosis in mice.
Product Specifications
CAS Number
1821379-62-7
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
S (C) (=O) (=O) O.CC=1C=C2C3=C4N (C2=CC1) CCN[C@@]4 (CCC3) [H]
Molecular Formula
C16H22N2O3S
Molecular Weight
322.42
Storage Conditions
-20°C
Notes
For research use only.
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