KL 465
KL 465 is a degrader of MAGE-A3. The degradation of MAGE-A3 caused by KL 465 leads to reduced viability of cancer cells, and this effect is dependent on the VHL protein.
Product Specifications
CAS Number
3057446-82-6
Field of Research
Pharmacology & Drug Discovery
Smiles
C (C=1C=C (C2=C3C (=CC=C2) NN=C3) C=CC1OCCOCCOC4=C (CNC (=O) [C@H]5N (C ([C@H] (C (C) C) N6C (=O) C=7C (C6) =CC=CC7) =O) C[C@H] (O) C5) C=CC (=C4) C8=C (C) N=CS8) N9CCN (C (=O) C%10=CC=CO%10) CC9
Molecular Formula
C56H60N8O9S
Molecular Weight
1021.19
Storage Conditions
-20°C
Notes
For research use only.
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