ATC-324
ATC-324 is a potent autophagy-targeting chimera (AUTOTAC) degrader of the androgen receptor (AR) with a DC50 of 2.05 μM. It induces autophagic-lysosomal degradation of AR, decreases nuclear AR and AR-V7 activity, and exhibits cytotoxic effects on AR-positive prostate cancer cells, making it useful for prostate cancer research.
Product Specifications
CAS Number
2925060-81-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
S=C1N (C (=O) C (C) (C) N1C2=CC (F) =C (C (NCCOCCOCCOCCOCCNC[C@H] (COC3=CC (OCC4=CC=C (F) C=C4) =C (OCC5=CC=C (F) C=C5) C=C3) O) =O) C=C2) C6=CC (C (F) (F) F) =C (C#N) C=C6
Molecular Formula
C53H55F6N5O10S
Molecular Weight
1068.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
T8199-30E-FITC 100 µL
Transferrin Receptor (CD71, TR, Tfr, TfnrR) (FITC) discontinued
Sign In for Pricing
View Details 
MBS280637-01 48 Tests
Horse NADH-ubiquinone oxidoreductase chain 4 (MT-ND4) ELISA Kit
Sign In for Pricing
View Details MBS280637-02 96 Tests
Horse NADH-ubiquinone oxidoreductase chain 4 (MT-ND4) ELISA Kit
Sign In for Pricing
View Details MBS280637-03 5x 96 Tests
Horse NADH-ubiquinone oxidoreductase chain 4 (MT-ND4) ELISA Kit
Sign In for Pricing
View Details MBS280637-04 10x 96 Tests
Horse NADH-ubiquinone oxidoreductase chain 4 (MT-ND4) ELISA Kit
Sign In for Pricing
View Details