RS47
RS47 (Compound 1a) is a small molecule (Kd = 1.1 μM) that specifically targets RelB, selectively inhibiting the non-canonical NF-κB pathway by disrupting RelB binding to target DNA. It exhibits antitumour activity in vivo and in vitro and may be used in studies of colorectal cancer and B-cell lymphoma.
Product Specifications
CAS Number
301655-16-3
Product Name Alternative
RS-47, RS 47
Field of Research
Signal Transduction
Purity
98.76% (May vary between batches)
Solubility
DMSO:20 mg/mL (56.43 mM)
Smiles
OC1=CC=C (O) C (=C1) C (=NNC=2N=CN=C3SC4=C (C32) CCCC4) C
Molecular Formula
C18H18N4O2S
Molecular Weight
354.43
Storage Conditions
-20°C
Notes
For research use only.
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