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Z57346765 hydrochloride

Z57346765 hydrochloride is an inhibitor of phosphoglycerate kinase 1 (PGK1) that binds to the ADP binding site, with a K\ (_D\) value of 2.09 x 10−5 M, thereby reducing the metabolic enzyme activity of PGK1, glucose consumption, and lactate production. Additionally, it inhibits DNA replication, impairs DNA damage repair, and induces cell cycle arrest in renal clear cell carcinoma (KIRC) cells.

Product Specifications

Smiles

OCCNC1=NC (NC2=CC=C (C) C=C2) =NC3=CC=CC=C31.Cl

Molecular Formula

C17H19ClN4O

Molecular Weight

330.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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