Tryptophan-cholic acid
Tryptophan-cholic acid (Trp-CA) is a microbial amino acid-binding bile acid (MABA), serving as an endogenous ligand and agonist for MRGPRE (Mas-related GPCR family member E), thereby inducing GLP-1 secretion. Tryptophan-cholic acid improves glucose tolerance in diabetic mice and may be utilised for studies on type 2 diabetes.
Product Specifications
CAS Number
1630745-39-9
Product Name Alternative
Trp-CA
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
>99.99% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.55 mM) ; DMSO:80 mg/mL (134.5 mM)
Smiles
O[C@H]1[C@]2 ([C@]3 ([C@@] (C) ([C@@] ([C@@H] (CCC (N[C@@H] (CC=4C=5C (NC4) =CC=CC5) C (O) =O) =O) C) (CC3) [H]) [C@@H] (O) C[C@@]2 ([C@]6 (C) [C@] (C1) (C[C@H] (O) CC6) [H]) [H]) [H]) [H]
Molecular Formula
C35H50N2O6
Molecular Weight
594.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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