TEAD1/3/4-IN-1
TEAD1/3/4-IN-1 (compound 1) is an inhibitor of TEAD1/3/4 that suppresses YAP/TAZ-TEAD interactions. It exhibits antitumour activity against NF2-deficient NCI-H226 cells and may be employed in studies of cancer and diseases mediated by Hippo pathway abnormalities.
Product Specifications
CAS Number
2762619-63-4
Product Name Alternative
TEAD1/3/4IN1
Field of Research
Stem Cell & Developmental Biology
Purity
99.25% (May vary between batches)
Solubility
DMSO:20 mg/mL (49.1 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (4.91 mM)
Smiles
O=C (C (F) =C) N1CC (N2C (=O) N (C3=CC=C (C=C3) C (F) (F) F) C4=NC=CN=C42) C1
Molecular Formula
C18H13F4N5O2
Molecular Weight
407.32
Storage Conditions
-20°C
Notes
For research use only.
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