2-PyriMidinaMine, 4-[3-fluoro-5- (4-Morpholinyl) phenyl
2-Pyridinamine, 4-[3-fluoro-5- (4-morpholinyl) phenyl] (Compound 9l) is an ATP-competitive JNK (c-Jun N-terminal kinase) inhibitor with IC50 values of 0.099 μM and 0.148 μM for JNK1 and JNK3 respectively, exhibiting the advantage of blood-brain barrier penetration. 2-Pyridinamine, 4-[3-fluoro-5- (4-morpholinyl) phenyl] inhibits c-Jun phosphorylation and reactive oxygen species (ROS) generation, making it suitable for neurodegenerative disease research.
Product Specifications
CAS Number
1128096-64-9
Product Name Alternative
2PyriMidinaMine,4[3fluoro5 (4Morpholinyl) phenyl
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
99.94% (May vary between batches)
Smiles
FC1=CC (=CC (=C1) N2CCOCC2) C3=NC (=NC=C3) NC4=CC=C (C=C4) N5N=C (N=C5) N6CCOCC6
Molecular Formula
C26H27FN8O2
Molecular Weight
502.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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