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Trimetazidine

Trimetazidine is a non-haemodynamic antianginal agent that selectively inhibits the mitochondrial enzyme 3-ketoacyl coenzyme A thiolase (LC 3-KAT), thereby preventing β-oxidation of free fatty acids, with an IC50 value of 75 nM. Trimetazidine prevents ischaemia-reperfusion injury by altering cardiac metabolism, exhibiting antioxidant and anti-ischaemic effects.

Product Specifications

CAS Number

5011-34-7

Product Name Alternative

Trimetazidine

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Purity

99.90% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (12.39 mM) ; DMSO:85 mg/mL (319.14 mM)

Smiles

COc1ccc (CN2CCNCC2) c (OC) c1OC

Molecular Formula

C14H22N2O3

Molecular Weight

266.34

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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