Bazedoxifene
Bazedoxifene is a non-steroidal, orally active selective estrogen receptor modulator that exhibits activity against ERα and ERβ with IC50 values of 26 nM and 99 nM, respectively. Bazedoxifene also inhibits IL-6/GP130 protein interactions. Bazedoxifene is utilized in research on postmenopausal osteoporosis and pancreatic cancer, serving as a dual-purpose compound for hormonal and cytokine pathway investigations.
Product Specifications
CAS Number
198481-32-2
Product Name Alternative
Bazedoxifene, TSE424, TSE-424
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.79% (May vary between batches)
Solubility
DMSO:80 mg/mL (169.99 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.01 mM)
Smiles
OC=1C=CC (=CC1) C2=C (C3=CC (O) =CC=C3N2CC4=CC=C (OCCN5CCCCCC5) C=C4) C
Molecular Formula
C30H34N2O3
Molecular Weight
470.61
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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