ABT-384
ABT-384 is a potent and selective 11β-HSD1 inhibitor, reducing enzyme activity in the liver and CNS. It modulates the HPA axis, increasing ACTH, cortisol, and sex hormones, supporting its investigation in preclinical models for Alzheimer's disease and major depressive disorder research.
Product Specifications
CAS Number
868623-40-9
Product Name Alternative
ABT 384, ABT384, ABT-384
Field of Research
Metabolism Research
Purity
99.86% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.05 mM) ; DMSO:24 mg/mL (48.62 mM)
Smiles
CC (C) (N1CCN (CC1) c1ccc (cn1) C (F) (F) F) C (=O) NC1C2CC3CC1CC (C3) (C2) C (N) =O
Molecular Formula
C25H34F3N5O2
Molecular Weight
493.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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