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Elsubrutinib

Elsubrutinib (ABBV-105) is a potent, selective, and irreversible Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 0.18 μM. This orally bioavailable small molecule is a valuable tool for investigating BTK's role in inflammatory and autoimmune disease pathways in both cellular and animal models.

Product Specifications

CAS Number

1643570-24-4

Product Name Alternative

ABBV105, ABBV-105, ABBV 105, Elsubrutinib

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.77% (May vary between batches)

Solubility

DMSO:80.00 mg/mL (269.03 mM)

Smiles

C (N) (=O) C1=C2C (=C (C=C1) [C@H]3CN (C (C=C) =O) CCC3) C=CN2

Molecular Formula

C17H19N3O2

Molecular Weight

297.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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