TH1834
TH1834 is a selective small-molecule inhibitor of the Tip60/KAT5 histone acetyltransferase. It triggers DNA damage and apoptosis in breast cancer cells like MCF-7, while sparing the related MOF acetyltransferase, making it a useful research tool for studying chromatin biology and cancer mechanisms in vitro.
Product Specifications
CAS Number
2108830-08-4
Product Name Alternative
TH1834, TH-1834, TH 1834
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
99.96% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.76 mM) ; DMSO:8 mg/mL (14.07 mM)
Smiles
O=C (O) CN1N=NC (=N1) C2=CC=C (C=C2) CN (CCC=3C=CC=CC3) CCCCOC4=CC=C (C=C4) CN5CCCC5
Molecular Formula
C33H40N6O3
Molecular Weight
568.71
Storage Conditions
-20°C
Notes
For research use only.
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