Ecopipam hydrochloride
Ecopipam (SCH 39166) hydrochloride is a highly potent, selective, and orally active antagonist of dopamine D1/D5 receptors. It exhibits impressive binding affinities, with Ki values of 1.2 nM and 2.0 nM for D1 and D5 receptors, respectively. Ecopipam hydrochloride demonstrates remarkable selectivity, displaying over 40-fold selectivity compared to D2, D4, 5-HT, and α2a receptors, with Ki values of 0.98 μM, 5.52 μM, 0.08 μM, and 0.73 μM, respectively. Its application extends to various areas of research, including schizophrenia, cocaine addiction, and obesity.
Product Specifications
CAS Number
190133-94-9
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
Cl.[H][C@]12CCc3ccccc3[C@]1 ([H]) c1cc (O) c (Cl) cc1CCN2C
Molecular Formula
C19H21Cl2NO
Molecular Weight
350.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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