PS372424 hydrochloride
PS372424 hydrochloride is a synthetic tripeptide agonist of the human CXCR3 receptor derived from CXCL10. It exhibits anti-inflammatory properties by inhibiting T-cell migration, as demonstrated in humanized models of arthritic inflammation. This compound is a valuable research tool for studying CXCR3-mediated immune responses in both in vitro and in vivo contexts.
Product Specifications
CAS Number
1596362-29-6
Product Name Alternative
PS 372424 hydrochloride
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
95.03% (May vary between batches)
Solubility
DMSO:200 mg/mL (319.9 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8 mM)
Smiles
C (N[C@H] (C (NCC1CCCCC1) =O) CCCNC (=N) N) (=O) [C@H]2N (C (CCC (=O) C3=CC=CC=C3) =O) CC=4C (C2) =CC=CC4.Cl
Molecular Formula
C33H45ClN6O4
Molecular Weight
625.2
Storage Conditions
-20°C
Notes
For research use only.
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