Methotrexate α-tert-butyl ester
Methotrexate α-tert-butyl ester is a protected analog of the antineoplastic and immunosuppressive drug methotrexate (MTX), in which the β-carboxyl group of the L-glutamate moiety is esterified with a tert-butyl group. Methotrexate α-tert-butyl ester is primarily used in chemical synthesis and prodrug development studies.
Product Specifications
CAS Number
79640-70-3
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.62% (May vary between batches)
Solubility
DMSO:80 mg/mL
Smiles
NC=1C2=C (N=C (N) N1) N=CC (CN (C) C3=CC=C (C (N[C@H] (C (OC (C) (C) C) =O) CCC (O) =O) =O) C=C3) =N2
Molecular Formula
C24H30N8O5
Molecular Weight
510.555
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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