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(+) -Norfenfluramine

(+) -Norfenfluramine, the principal hepatic metabolite of (+) -fenfluramine, acts as a selective agonist for the 5-HT2B receptor, exhibiting a potent K i of 11.2 nM. It significantly promotes the hydrolysis of inositol phosphates and heightens intracellular Ca2+ levels. This compound is valuable in the study of primary pulmonary hypertension and valvular heart disease.

Product Specifications

CAS Number

19036-73-8

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

C[C@H] (N) Cc1cccc (c1) C (F) (F) F

Molecular Formula

C10H12F3N

Molecular Weight

203.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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