Metrifonate
Metrifonate is an organophosphorus prodrug that is metabolised non-enzymatically in the body to DDVP (dichlorvos), which acts as an irreversible cholinesterase (ChE) inhibitor. It inactivates ChE by phosphorylating the serine residue at its active site, making it useful for treating Alzheimer's disease and as an insecticide. Metrifonate affects AChE activity, oxidative stress, neurotoxicity, and cortisol levels in carp.
Product Specifications
CAS Number
52-68-6
Product Name Alternative
Trichlorfon
Field of Research
Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery
Solubility
H2O:20 mg/mL (77.69 mM)
Smiles
O=P (OC) (OC) C (O) C (Cl) (Cl) Cl
Molecular Formula
C4H8Cl3O4P
Molecular Weight
257.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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