TMPD (dihydrochloride)

TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases[1][2]. TMPD dihydrochloride is also a complex IV substrate[3].

Product Specifications

CAS Number

[637-01-4]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/tmpd-dihydrochloride.html

Purity

98.81

Solubility

DMSO : 16.67 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

CN(C)C1=CC=C(N(C)C)C=C1.[H]Cl.[H]Cl

Molecular Formula

C10H18Cl2N2

Molecular Weight

237.17

Precautions

H315, H319

References & Citations

[1]S Kuss, et al. Electrochemical recognition and quantification of cytochrome c expression in Bacillus subtilis and aerobe/anaerobe Escherichia coli using N, N, N', N'-tetramethyl- para-phenylene-diamine (TMPD) . Chem Sci. 2017 Nov 1;8 (11) :7682-7688.|[2]Nenad Petrovic, et al. Using N, N, N', N'-tetramethyl-p-phenylenediamine (TMPD) to assay cyclooxygenase activity in vitro. Methods Mol Biol. 2010;594:129-40.|[3]Franco A Rossato, et al. Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic melan-a cells associated with inhibition of mitochondrial respiration. PLoS One. 2014 Jun 25;9 (6) :e101060.