Diphenylpyraline

Diphenylpyraline is a potent histamine H1 receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al[1].

Product Specifications

CAS Number

[147-20-6]

UNSPSC

12352005

Hazard Statement

H302

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/diphenylpyraline.html

Purity

98.60

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN(CC1)CCC1OC(C2=CC=CC=C2)C3=CC=CC=C3

Molecular Formula

C19H23NO

Molecular Weight

281.39

Precautions

H302

References & Citations

[1]Erik B Oleson, et al. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward.|[2]Gennady B Lapa, et al. Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties.