Diphenylpyraline
Diphenylpyraline is a potent histamine H1 receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al[1].
Product Specifications
CAS Number
147-20-6
UNSPSC
12352005
Hazard Statement
H302
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/diphenylpyraline.html
Purity
98.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(CC1)CCC1OC(C2=CC=CC=C2)C3=CC=CC=C3
Molecular Formula
C19H23NO
Molecular Weight
281.39
Precautions
H302
References & Citations
[1]Erik B Oleson, et al. Effects of the histamine H₁ receptor antagonist and benztropine analog diphenylpyraline on dopamine uptake, locomotion and reward.|[2]Gennady B Lapa, et al. Diphenylpyraline, a histamine H1 receptor antagonist, has psychostimulant properties.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor
Available Sizes
Frequently Asked Questions
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