DL-Penicillamine

DL-Penicillamine [ (±) -Penicillamine] is a copper chelating agent. DL-Penicillamine has antidotal effects in thallotoxicosis rats when co-treated with Prussian blue (HY-106594A) . DL-Penicillamine can cause pyridoxine deficiency and then induce optic axial neuritis. DL-Penicillamine can also depress primary immune response[1][2][3].

Product Specifications

CAS Number

[52-66-4]

Product Name Alternative

(±) -Penicillamine

UNSPSC

12352211

Hazard Statement

H315, H319, H372, H413

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dl-penicillamine.html

Concentration

10mM

Purity

98.0

Solubility

H2O : 33.33 mg/mL (ultrasonic)

Smiles

CC(C(N)C(O)=O)(S)C

Molecular Formula

C5H11NO2S

Molecular Weight

149.22

Precautions

H315, H319, H372, H413

References & Citations

[1]TU J, BLACKWELL RQ, LEE PF. DL-penicillamine as a cause of optic axial neuritis. JAMA. 1963 Jul 13;185:83-6.|[2]Montes S, et al. Additive effect of DL-penicillamine plus Prussian blue for the antidotal treatment of thallotoxicosis in rats. Environ Toxicol Pharmacol. 2011 Nov;32 (3) :349-55.|[3]Huebner Kf, Gengozian N. Depression Of The Primary Immune Response By Dl-Penicillamine. Proc Soc Exp Biol Med. 1965 Feb;118:561-5.