Cimifugin
Cimifugin (Cimitin) is a bioactive component of Cimicifuga racemosa, a Chinese herb. Cimifugin suppresses allergic inflammation by reducing epithelial derived initiative key factors via regulating tight junctions[1]. Cimifugin reduces the migration and chemotaxis of RAW264.7 cells and inhibits the release of inflammatory factors and activation of MAPKs and NF-κB signaling pathways induced by LPS[2].
Product Specifications
CAS Number
[37921-38-3]
Product Name Alternative
Cimitin
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Cimifugin.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)
Smiles
O=C1C=C(CO)OC2=CC(O[C@H](C(C)(O)C)C3)=C3C(OC)=C12
Molecular Formula
C16H18O6
Molecular Weight
306.31
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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