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Gypsetin

Gypsetin inhibits the activity of acyl-CoA:cholesterol acyltransferase (ACAT), showing inhibitory effects on rat liver microsomal ACAT with an IC50 of 18 μM, and competes with oleoyl-CoA substrate, possessing a Ki value of 5.5 μM. Additionally, Gypsetin prevents the formation of cholesterol esters from oleic acid with an IC50 of 0.65 μM.

Product Specifications

CAS Number

155114-38-8

Field of Research

Metabolism Research

Smiles

[C@@] (C=C) (C) (C) [C@]12[C@] (O) (C=3C (N1) =CC=CC3) C[C@@]4 (N2C (=O) [C@]5 (N (C4=O) [C@]6 (C (C=C) (C) C) [C@] (O) (C5) C=7C (N6) =CC=CC7) [H]) [H]

Molecular Formula

C32H36N4O4

Molecular Weight

540.653

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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