Gypsetin
Gypsetin inhibits the activity of acyl-CoA:cholesterol acyltransferase (ACAT), showing inhibitory effects on rat liver microsomal ACAT with an IC50 of 18 μM, and competes with oleoyl-CoA substrate, possessing a Ki value of 5.5 μM. Additionally, Gypsetin prevents the formation of cholesterol esters from oleic acid with an IC50 of 0.65 μM.
Product Specifications
CAS Number
155114-38-8
Field of Research
Metabolism Research
Smiles
[C@@] (C=C) (C) (C) [C@]12[C@] (O) (C=3C (N1) =CC=CC3) C[C@@]4 (N2C (=O) [C@]5 (N (C4=O) [C@]6 (C (C=C) (C) C) [C@] (O) (C5) C=7C (N6) =CC=CC7) [H]) [H]
Molecular Formula
C32H36N4O4
Molecular Weight
540.653
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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