Antcin B
Antcin B is an inhibitor of SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) . It interacts with several crucial amino acid residues of 3CL Pro, including Leu141, Asn142, Glu166, and His163, through hydrogen bonding, salt bridges, and hydrophobic interactions, thereby inhibiting its activity. This inhibition blocks the cleavage of viral polyproteins and suppresses the replication of the SARS-CoV-2 virus within host cells. Antcin B shows potential for research in the context of COVID-19.
Product Specifications
CAS Number
163597-25-9
Field of Research
Infectious Disease & Virology
Smiles
C[C@@]12C3=C ([C@]4 ([C@] (C) (CC3=O) [C@@] ([C@@H] (CCC (C (C (O) =O) C) =C) C) (CC4) [H]) [H]) C (=O) C[C@]1 ([C@H] (C) C (=O) CC2) [H]
Molecular Formula
C29H40O5
Molecular Weight
468.625
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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