Triptriolide
Triptriolide inhibits puromycin aminonucleoside (PAN) -induced apoptosis in mouse podocytes by modulating Bcl-2 family proteins and suppressing Caspase-3. It also promotes cell survival and protects podocyte function by activating the TAK1-NF-κB signaling pathway and upregulating the podocyte protein podocin.
Product Specifications
CAS Number
137131-18-1
Field of Research
Cell Biology, Signal Transduction
Smiles
C[C@@]12[C@@]34[C@@]5 ([C@@] (O5) (C[C@]1 (C6=C (CC2) C (=O) OC6) [H]) [H]) [C@H] (O) [C@@] ([C@@H] (C) C) (O) [C@H] (O) [C@@]3 (O4) [H]
Molecular Formula
C20H26O7
Molecular Weight
378.416
Storage Conditions
-20°C
Notes
For research use only.
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