Bleformin A
Bleformin A is a potent BChE inhibitor with an IC50 value of 5.2 μM. Bleformin A is a nature product that could be isolated from Bletilla striata. Bleformin A can be used for research of Alzheimer's disease (AD) [1].
Product Specifications
CAS Number
1980064-35-4
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bleformin-a.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1CC2=C3C(C(C(OC)=C(OC)C(O)=C4)=C4C=C3)=CC=C2O
Molecular Formula
C23H20O5
Molecular Weight
376.40
References & Citations
[1]Liu Y, et, al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12 (1) :13649.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
BChE
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